Our immune system has to recognize and destroy pathogens and tolerate nonharmful molecules of the body. T cells – sentinels of the immune system - play a key role in this process.
Immunotherapy has revolutionized cancer treatment. However, only one-third of patients respond
to the treatment. As these drugs are very expensive, it is of utmost importance to identify
biomarkers that can accurately predict response.
The human immune system plays a fundamental role in killing pathogens and tumors, while it is essential to tolerate healthy cells of the human body. Tumor immunotherapy has revolutionized cancer treatment in the previous two decades.