Thomas Vogl at MedUni Wien is leading a project funded by an ERC Starting Grant, focusing on the interaction between the human immune system and the gut microbiome. His research, "EarlyMicroAbs," aims to understand how antibodies targeting intestinal bacteria affect immune development and health outcomes. Vogl's team is using advanced techniques to study nearly 600,000 microbiome antigens, offering insights into antibody targets and their roles in disease and therapy. This work could lead to new treatments by elucidating the complex interplay between gut microbes and the immune system.
The Balázs Papp Laboratory focuses on systems biology, particularly understanding the robustness and evolution of cellular metabolism. They combine experimental and computational approaches to investigate how metabolic networks withstand genetic perturbations and adapt to new environments, contributing to the broader understanding of cellular function and evolution.
The BioMAG Lab leverages recent advancements in systems biology, lab automation, and high-throughput microscopy to explore complex biological systems through high-throughput light microscopy. With modern equipment generating vast data volumes, the lab addresses the challenge of manual analysis infeasibility by focusing on automating this process. Their research intersects biology and computer science, utilizing both wet-lab techniques and light microscopy, alongside image analysis and machine learning methods, to devise computational solutions for biological problems.