The Systems Immunology Research Group is proud to be a part of the EU Horizon Health consortium „ID-DarkMatter-NCD.”
We are delighted to announce that our research group is a member of an exceptional team, led by Thomas Vogl and composed of experts in immunology, genomics, and data science. This team has been honored with the prestigious HORIZON-HLTH-2023-DISEASE-03 grant for the project named ID-DarkMatter-NCD. The primary focus of this project is to unravel the mysterious link between infectious diseases (IDs) and immune-related noncommunicable diseases (IR-NCDs).
The key objectives of the project include identifying the IDs responsible for triggering IR-NCDs and disentangling the genetic and environmental factors influencing the transition from IDs to IR-NCDs. To accomplish these goals, the team plans to screen for antibody responses against an impressive 600,000 antigens in 6,000 patients.
The diseases selected for in-depth analysis comprise post-COVID-19-condition, multiple sclerosis, chronic fatigue syndrome, rheumatoid arthritis, lupus, and inflammatory bowel disease. The team will employ cutting-edge multi-omics approaches and personalized genotyping of human leukocyte antigen (HLA) and adaptive immune receptor genes to gain a comprehensive understanding of each patient’s immune profile.
We eagerly anticipate collaborating on this project with outstanding researchers.